Sin separates us from God, only through Accepting Christ and believing in Him and His sacrifice can there be any communication between us and God. All sin debt belongs to God, Christ paid the ransom for us. And even when you have been saved there will be periods where you might think God does not hear our prayers, where has He gone? He is with us but He desires that we "thirst" for Him, "hunger" for Him, lest we become complacent in our Faith and forget that we are to regard the matter of our salvation in "fear and trembling."
Phillipians 2:12 (kjv)
"Wherefore, my beloved, as ye have always obeyed, not as in my presence only, but now much more in my absence, work out your own salvation with fear and trembling."